Hepato-pancreatic fat-fetuin A based axis in context of diabetes and its reversal

Recent research has focused on reversing type 2 diabetes mellitus (T2DM) via lifestyle-related approaches, including low-calorie diets. Metabolic parameters such as fat accumulation in the liver and pancreas have garnered much attention this context. Pancreatic been linked with adverse metabolic consequences T2DM syndrome. Obesity is primary factor leading to ectopic organs pancreas. This review examines potential role of pancreatic pathogenesis whether it can be a target chronic condition.